Technetium-99m labeled peptides for imaging

Details Technetium-99m labeled peptides for imaging Technetium-99m labeled peptides for imaging

1995-06-06

1998-07-07

Kight, John

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 165, 424 111, 534 10, 534 14, 530300, A61K 5100, A61M 3614

Patent

active

057764280

ABSTRACT:
This invention relates to radiolabeled peptides and methods for producing such peptides. Specifically, the invention relates to peptides, methods and kits for making such peptides, and methods for using such peptides to image sites in a mammalian body labeled with technetium-99m (Tc-99m) via a radiolabel-binding moiety which forms a neutral complex with Tc-99m.

REFERENCES:
patent: 4434151 (1984-02-01), Byrne et al.
patent: 4444690 (1984-04-01), Fritzberg
patent: 4571430 (1986-02-01), Byrne et al.
patent: 4575556 (1986-03-01), Byrne et al.
patent: 4673562 (1987-06-01), Davison et al.
patent: 4832940 (1989-05-01), Ege et al.
patent: 4861869 (1989-08-01), Nicolotti et al.
patent: 4965392 (1990-10-01), Fritzberg et al.
patent: 4986979 (1991-01-01), Morgan, Jr. et al.
patent: 5061641 (1991-10-01), Schochat et al.
patent: 5175343 (1992-12-01), Fritzberg et al.
patent: 5242679 (1993-09-01), Fritzberg et al.
patent: 5326856 (1994-07-01), Coughlin et al.
patent: 5376356 (1994-12-01), Morgan, Jr.
patent: 5527885 (1996-06-01), Coughlin et al.
Tubis et al., "The Preparation of .sup.99m Technetium-Labeled Cystine, Methionine and a Synthetic Polypeptide and their Distribution in Mice," Int. J. Appl. Rad. Isot. 19:835-840 (1968) Month not provided with publications. Characterization and Chemical Quality Control by Ampholyte Displacement Radiochromatography," Int. J. Appl. Rad. Isot. 34:1003 (1983) Month not provided with publications.
Baidoo & Lever, 1990, "Synthesis of a Diaminedithiol Bifunctional Chelating Agent for Incorporation of Technetium-99m into Biomolecules," Bioconjugate Chem. 1:132-137 Month not provided with publications.
Bryson et al., "Neutral Technetium(V) Complexes with Amide-Thiol-Thioether Chelating Ligands," Inorg. Chem. 27:2154-2161 (1988).
Misra et al., 1989, "Synthesis of a Novel Diaminodithiol Ligand For Labeling Proteins and Small Molecules with Technetium-99m," Tet. Let. 30:1885-1888 Month not provided with publications.
Bryson et al., "Protecting Groups in the Preparation of Thiolate Complexes of Technetium," Inorg. Chem. 29:2948-2951 (1990) Month not provided with publications. Tracer of Local Cerebral Blood Flow," J. Nucl. Med. 31:885 (1990) Month not provided with publications.

Affiliated with

Also associated with

Rating

Technetium-99m labeled peptides for imaging does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Technetium-99m labeled peptides for imaging, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Technetium-99m labeled peptides for imaging will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1202387