Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1986-10-14
1987-12-22
Terapane, John F.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
534 14, 564258, 564267, 564268, A61K 4300, C07F 1300
Patent
active
047146052
ABSTRACT:
Technetium-99m labeled dioxime complexes are useful for imaging the myocardium, brain and hepatobiliary system, in humans and other mammalian species.
REFERENCES:
Boston et al., "Encapsulation Reaction. Synthesis of the Clathro Chelate 1,8-Bis(fluoroboro)-2,7,9,14,15,20-hexaoxa-3,6,10,13,16,19-hexaaza-4,5,11, 12,17,18-hexamethylbicyclo[6.6.6]eicosa-3,5,10,12,16,18-hexaenecobalt(III) ion", J.A.C.S., 90:6859-6860, (1968).
Boston et al., "Encapsulation Reactions. Synthesis and Study of Clathro Chelates Derived from Dimethylglyoxime, Cobalt, and Lewis Acids", J.A.C.S., 95(13):4163 (1973).
Simek, "Herstellung Von Kalium-Und Natriumdimethylglyoximatoniccolat(IV)", Collection Czechoslov. Chem. Comm., 27:220 (1962).
Robbins et al., "Synthesis and Electrochemistry of Iron(II)Clathrochelates", Inorg. Chem., 24(21):3381 (1985).
Feld Thomas A.
Juri Pedro N.
Treher Elizabeth N.
Barrack Donald J.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Mallon M. L.
Terapane John F.
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