Technetium-99m generators

Radiant energy – Fluent material containment – support or transfer means – With irradiating source or radiating fluent material

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2523011R, 422159, 423 2, 423249, G21G 104, C01G 5700

Patent

active

042800536

ABSTRACT:
A Technetium-99m generator has a matrix having a compound of molybdenum-99 bound into or forming the matrix, the compound of the molybdenum-99 being substantially insoluble in an eluant which can be used in a radiopharmaceutical and the molybdenum compound permitting diffusion of technetium-99m therethrough and elution therefrom. The molybdenum compound can be a monomolybdate, an isopolymolybdate or a heteropolymolybdate and zirconium molybdate is preferred although other cation molybdates may be used. Methods of preparation of the generator include dissolving irradiated molybdenum trioxide in alkaline solution and precipitating the molybdate at a selected pH and packing the precipitate in finely divided form into a column. Alternatively the generator may be formed from a non-radioactive, molybdenum compound and activated later when desired by passing a solution of a compound of molybdenum-99 through the column.

REFERENCES:
patent: 3785990 (1974-01-01), Benjamins et al.
Tanase, M., "Separation of .sup.99m Tc from Neutron-Irradiated MoO.sub.3 . . . ", J. Radioanal. Chem., 1977, 41(1) 23-27, (Jan. 1977).
Levi, H. W. et al., "Removal of .sup.99 Tc from .sup.99 Mo-containing Ammonium Molybdatophosphate", Chem. Abstracts 67: 112929z, (1967).

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