Tear film measurement

Optics: eye examining – vision testing and correcting – Eye examining or testing instrument – Objective type

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07988294

ABSTRACT:
The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer. In order to facilitate ease of measurement, the patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the patient's eye.

REFERENCES:
patent: 4747683 (1988-05-01), Doane
patent: 4842401 (1989-06-01), Maurice
patent: 4938584 (1990-07-01), Suematsu et al.
patent: D330769 (1992-11-01), Blaha et al.
patent: 5621523 (1997-04-01), Oobayashi et al.
patent: 5642137 (1997-06-01), Kitazumi
patent: 5647032 (1997-07-01), Jutamulia
patent: 5719659 (1998-02-01), Suzuki
patent: D394505 (1998-05-01), Hayashi
patent: 5886767 (1999-03-01), Snook
patent: 5988815 (1999-11-01), Maus et al.
patent: 6198540 (2001-03-01), Ueda et al.
patent: 6236459 (2001-05-01), Negahdaripour et al.
patent: 6299305 (2001-10-01), Miwa
patent: 6394603 (2002-05-01), Miwa et al.
patent: 6447119 (2002-09-01), Stewart et al.
patent: D465850 (2002-11-01), Takizawa
patent: D472637 (2003-04-01), Cooper et al.
patent: 6659613 (2003-12-01), Applegate et al.
patent: 6685320 (2004-02-01), Hirohara et al.
patent: 6736507 (2004-05-01), Kudryashov et al.
patent: 7073906 (2006-07-01), Portney
patent: 7121666 (2006-10-01), Tseng et al.
patent: D552736 (2007-10-01), Yamaoka
patent: D582556 (2008-12-01), Yamaoka
patent: D607562 (2010-01-01), Heine et al.
patent: 7654669 (2010-02-01), Suzuki
patent: 7688453 (2010-03-01), Williby et al.
patent: 7758190 (2010-07-01), Korb et al.
patent: 7771353 (2010-08-01), Luce
patent: 2002/0180929 (2002-12-01), Tseng et al.
patent: 2003/0056281 (2003-03-01), Hasegawa
patent: 2004/0212781 (2004-10-01), Mihashi et al.
patent: 2006/0055956 (2006-03-01), Takahashi et al.
patent: 2006/0109423 (2006-05-01), Wang
patent: 2006/0140454 (2006-06-01), Northcott et al.
patent: 2008/0273171 (2008-11-01), Huth et al.
patent: 2008/0316499 (2008-12-01), Korb et al.
patent: 2008/0319323 (2008-12-01), Gravely et al.
patent: 2009/0201465 (2009-08-01), Huth
patent: 2009/0225276 (2009-09-01), Suzuki
patent: 2010/0259721 (2010-10-01), Korb et al.
patent: 0943288 (1999-09-01), None
patent: 1900320 (2008-03-01), None
patent: 2189108 (2010-05-01), None
patent: 2407378 (2006-09-01), None
patent: 8052112 (1996-02-01), None
patent: 2009134276 (2009-06-01), None
patent: 0026614 (2000-05-01), None
patent: 2005044099 (2005-05-01), None
patent: 2008137863 (2008-11-01), None
1994-Korb, “Tear Film Lipid Layer Thickness as a Function of Blinking”.
Kojima, Takashi et al.., “A New Noninvasive Tear Stability Analysis System for the Assessment of Dry Eyes,” Investigative Ophthalmology & Visual Science, May 2004, vol. 45, No. 5, pp. 1369-1374.
Arndt, G. Dickey et al., “Microwave Treatment of Prostate Cancer and Hyperplasia,” NASA Tech Briefs, Jun. 2005, 1 page.
King-Smith, P. Ewen et al., “The Thickness of the Human Precorneal Tear Film: Evidence from Reflection Spectra,” Investigative Ophthalmology & Visual Science, Oct. 2000, vol. 41, No. 11, 12 pages.
Nichols, Jason J. et al., “The Thickness of the Post-Lens Tear Film Measured by Interferometry,” Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3, Edited by D. Sullivan et al., Kluwer Academic / Plenum Publishers, 2002, 5 pages.
Borchman, Douglas, et al., “Temperature-Induced Conformational Changes in Human Tear Lipids Hydrocarbon Chains” Biopolymers, vol. 87, No. 2-3, Jun. 13, 2007, pp. 124-133 (10 pages).
Cruz, Daniele, “Surgeon: Early Treatment Key to Avoiding Dry Eye Progression” Ocular Surgery News, U.S. Edition, May 2007, 1 page.
Fouks, Gary N., MD, Facs, “The Correlation Between the Tear Film Lipid Layer and Dry Eye Disease” Major Review, Survey of Ophthalmology, vol. 52, No. 4, Jul.-Aug. 2007, 6 pages. (pp. 369-374).
Korb, Donald R., OD, et al., “A Device to Standardize and Quantify the Force Used to Diagnose Meibomian Gland Obstruction and Dysfunction” 2007, 1 page.
Korb, Donald R., OD, et al., “A New Device for the Diagnosis of Meibomian Gland Dysfunction and Obstruction” 2007, 1 page.
Kronemyer, Bob, “Dry Eye Experts Unveil New Treatment Guidelines, Terminology” Ocular Surgery News, U.S. Edition, May 2007, 1 page.
Alonso-Caneiro, D. et al., “Context-Based Modelling of Interferometric Signals for the Assessment of Tear-Film Surface Quality,” 2009 IEEE/SP 15th Workshop on Statistical Signal Processing (SSP), 2009, pp. 553-556.
Finnemore, VM et al., “Flourescein Dye Concentration as a Factor in Tear Film Flourescence,” in Sullivan DA (ed): Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance, Adv. Exp. Med. Biol., No. 438, 1998, pp. 875-878.
Korb, Donald, “Survey of Preferred tests for Diagnosis of the Tear Film and Dry Eye,” Cornea, vol. 19, 2000, pp. 483-486.
Behrens, Ashley, MD, “Multiwave Interferometry is Creating a New Understanding of the Tear Film,” Refractive Eyecare, Oct. 2009, from www.refractiveeyecare.com, 5 pages.
An, Yang et al., “Contrast Sensitivity Measurement in Dry Eyes,” Int J Ophthalmol, vol. 10, No. 3, Mar. 2010, pp. 488-491.
Prydal, Jeremy I. et al., “Study of Human Precorneal Tear Film Thickness and Structure Using Laser Interferometry,” Investigative Ophthalmology & Visual Science, vol. 33, No. 6, May 1992, pp. 2006-2011.
Guillon, Jean-Pierre, “Non-Invasive Tearscope Plus Routine for Contact Lens Fitting,” Contact Lens and Anterior Eye, (Supplement) 21, 1998, pp. S31-S40.
Korb, Donald R. et al., “Meibomian Gland Diagnostic Expressibility: Correlation With Dry Eye Symptoms and Gland Location,” Cornea, vol. 27, No. 10, Dec. 2008, pp. 1142-1147.
Guillon, Jean-Pierre, “Use of the Tearscope Plus and Attachments in the Routine Examination of the Marginal Dry Eye Contact Lens Patient,” Lacrimal Gland, Tear Film, and Dry Eye Syndrome 2, 1998, pp. 859-867.
Rolando, M. et al., “New Test to Quantify Lipid Layer Behavior in Healthy Subjects and Patients with Keratoconjunctivitis Sicca,” Cornea, vol. 8, No. 27, Sep. 2008, pp. 866-870.
Uchida, A. et al., “Nonivasive Interference Tear Meniscometry in Dry Eye Patients with Sjogren Syndrome,” Am. J. Ophthalmol., vol. 144, No. 2, Aug. 2007, pp. 232-237.
Behrens, Ashley, MD, “Interferometry for the Detection of Dry Eye,” Cataract & Refractive Surgery Today Europe, Nov./Dec. 2008. pp. 57-58.
Lopez Garcia, J.S. et al., “Measure of the Fatty Layer Thickness of Precorneal Tear Film by Interference Colours in Different Types of Dry Eye,” Sociedad Espanola de Oftalmologia, vol. 78, Part 5, Jan. 2003, pp. 257-264.
Prydal, J.I. et al., “Study of Precorneal Tear Film Thickness and Structure by Interferometry and Confocal Microscopy,” Investigative Ophthalmology and Visual Science, vol. 33, No. 6, May 1992, pp. 1996-2005.
Prydal, J.I. et al., “In Vivo Confocal Microscopy of the Cornea and Tear Film,” Scanning, vol. 17, 1995, pp. 133-135.
Mathers, W.D., “Assessment of the Tear Film with Tandem Scanning Confocal Microscopy,” Cornea, vo

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Tear film measurement does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tear film measurement, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tear film measurement will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2787377

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.