Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-12-20
2000-10-24
Campell, Bruce R.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 435325, 536 231, 536 235, C12D 2100, C12N 121, C12N 1563, C12N 1585
Patent
active
061365564
ABSTRACT:
Novel response regulator polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides and polypeptides for the treatment of infection, particularly bacterial infections. Antagonists against such the polypeptides of the invention and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence the nucleic acid sequences and the polypeptides of the invention in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding response regulators and for detecting the polypeptide in a host.
REFERENCES:
patent: 5545717 (1996-08-01), Weissbach
Ichinose. Biochemistry 31(12): 3113-3118, especially Fig. 3, p.3115; and p. 3113, column 2, first full paragraph, 1992.
Seki, et al., Cloning and Nucleotide Sequence of phoP, the Regulatory Gene for Alkaline Phosphatase and Phosphodiesterase in Bacillus subtilis, Journal of Bacteriology, 169(7), pp. 2913-2916, 1987.
Ascension No. P13792, Dec. 4, 1992, Lee, et al., Nucleotide sequence of the phoP gene encoding PhoP, the response regulator of the phosphate regulon of Bacillus subtilis.
Bayles, "The use of degenerate, sensor gene-specific, oligodeoxyribonucleotide primers to amplify DNA fragments from Staphylococcus aureus", Gene, 123, gs. 99-103, 1993.
Volz, "Structural Conservation in the CheY Superfamily", Biochemistry, 32(44), pp. 11741-11753, 1993.
Hodgson John Edward
Wallis Nicola Gail
Campell Bruce R.
Deibert Thomas S.
Gimmi Edward R.
King William T.
Schnizer Richard
LandOfFree
TCTS response regulator does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with TCTS response regulator, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and TCTS response regulator will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1962247