Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1996-12-20
2000-07-04
Minnifield, Nita
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 536 234, 536 2431, 435 691, 4352523, 435883, 530350, 935 1, 935 19, 4242431, C07H 2100, C07H 2104, C12P 2106, A61K 39085
Patent
active
060840862
ABSTRACT:
Novel response regulator polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides and polypeptides for the treatment of infection, particularly bacterial infections. Antagonists against such the polypeptides of the invention and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence the nucleic acid sequences and the polypeptides of the invention in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding response regulators and for detecting the polypeptide in a host.
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Hodgson John Edward
Wallis Nicola Gail
Deibert Thomas S.
Gimmi Edward R.
King William T.
Minnifield Nita
SmithKline Beecham p.l.c.
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