Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-10-27
1999-11-16
Degen, Nancy
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 701, 435 711, 435 911, 435 914, 4353201, 536 231, 536 241, C12P 2102, C07H 2104, C12N 1512, C12N 1585
Patent
active
059855983
ABSTRACT:
The present invention relates to nucleotide sequences of TCL-1 genes and amino acid sequences of their encoded proteins, as well as derivatives and analogs thereof, and antibodies thereto. The TCL-1 gene sequence is preferentially expressed early in T and B lymphocyte differentiation. The present invention further relates to the use of TCL-1 genes and their encoded proteins as diagnostic and therapeutic reagents for the detection and treatment of disease states associated with chromosomal abnormalities.
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Croce Carlo M.
Russo Giandomenico
Degen Nancy
Raggio-Italgene S.p.A.
Thomas Jefferson University
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