tcdB2 protein from Photorhabdus luminescens W-14

Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se – Higher plant – seedling – plant seed – or plant part

Reexamination Certificate

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C536S023700, C435S418000, C435S070100

Reexamination Certificate

active

10706424

ABSTRACT:
TcdB2, a protein fromPhotorhabdus luminescensW-14, and nucleotide sequences encoding TcdB2, are useful for enhancing expression of orally activePhotorhabdus luminescensinsecticidal toxins in heterologous organisms.

REFERENCES:
patent: 6281413 (2001-08-01), Kramer et al.
patent: 2002/0078478 (2002-06-01), Ffrench-Constant et al.
patent: WO 01/11029 (2001-02-01), None
Waterfield et al 2001, Trends Microbiol. 9:185-191.
Waterfield et al 2001, Appl. Environ. Microbiol. 67:5017-5024.
DATABASE EMBL ′Online! , Oct. 27, 2001, XP002290086 retrieved from EBI Database accession No. AF346500 abstract.
Waterfield N. R. et. al.: “The tc genes of Photorhabdus: A growing family” Trends in Microbiology, Elsevier Science Ltd., Kidlington, GB, vol. 9, No. 4, Apr. 2001, pp. 181-191 xp002221683.
Ffrench-Constant R H et al: “A genomic sample sequence of the entomopathogenic bacteriumPhotorhabdus luminescensW14: Potential implications for virulence” Applied and Environmental Microbiology, Washington, DC US, vol. 66, No. 8, Aug. 2000, pp. 3310-3329.
Waterfield N. et al: “Oral toxicity ofPhotorhabdus luminescensW14 toxin complexes inEscherichia coli” Applied Environmental Microbiology, Washington, DC, US, vol. 67, No. 11, Nov. 2001, pp. 5017-5024.
Ffrench-Constant R et al: “Photorohabdus toxins: novel biological insecticides.” Current Opinion in Microbiology. Jun. 1999, vol. 2, No. 3, Jun. 1999, pp. 284-228.
Ffrence-Constant R H et al: “Novel insecticidal toxins from nematode-symbiotic bacteria” CMLS Cellular and Molecular Life Sciences, vol. 57, No. 5, May 2000, pp. 828-833.
Waterfield Nicholas R et al: “Genomic islands in Photorhabdus.” Trends in Microbiology, vol. 10, No. 12, Dec. 2002, pp. 541-545.

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