Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-04-11
1982-01-12
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424330, A61K 3133, A61K 31135
Patent
active
043105246
ABSTRACT:
A method is provided for treating depression in a patient therefrom and requiring rapid symptomatic relief, which comprises administering to said patient concurrently (a) an effective antidepressant amount of a tricyclic antidepressant or a pharmaceutically effective acid addition salt thereof, and (b) an amount of an .alpha.-adrenergic receptor blocking agent effective to achieve rapid onset of the antidepressant action of (a), whereby the onset of said antidepressant action is achieved within from 1 to 7 days.
A pharmaceutical composition is also provided which is especially adapted for use with the foregoing method.
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Chemical Abst., vol. 66-72828m, (1967), Kellett.
Chemical Abst., vol. 68-94371a, (1968), Martelli et al.
Chemical Abst., vol. 74-86048j, (1971), Dixit et al.
Holmberg et al., Psychopharm., 2, 93 (1961).
Svensson, Symp. Med. Hoechst., 13, 245 (1978).
McMillen et al., Fed. Proc., 38, 592 (1979).
Sellinger et al., Fed. Proc., 38, 592 (1979).
Pandey et al., Fed. Proc., 38, 592 (1979).
Ursillo Richard C.
Wiech Norbert L.
Friedman Stanley J.
Richardson-Merrell Inc.
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