Tc99m-Phenida, radioscintigraphic agent for diagnosis of hepaton

Details Tc99m-Phenida, radioscintigraphic agent for diagnosis of hepaton Tc99m-Phenida, radioscintigraphic agent for diagnosis of hepaton

1982-08-30

1984-06-12

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

260429R, 422 61, 564 50, 564 53, 564 59, 564195, 548163, 548180, A61K 4300, A61K 4900

Patent

active

044541074

ABSTRACT:
This invention relates to novel derivatives of imino diacetic acid of the formula: ##STR1## wherein R.sup.1 is selected from the group consisting of: ##STR2## wherein X is halo (chloro, bromo or iodo) and R.sup.2 is lower alkyl of from 1-5 carbon atoms. It also relates to a novel diagnostic kit for hepatobiliary imaging comprising ingredients employed in the intravenous injection of a complex of technetium 99m, and an imino diacetic acid of the above formula. It also relates to a process for preparing said compounds by reaction of nitrilotriacetic acid anhydride and an amine of the formula R.sup.1 NH.sub.2 wherein R.sup.1 is as defined hereinabove.

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