Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide contains a tissue – organ – or cell...
Reexamination Certificate
2007-01-03
2011-11-08
Fox, David T (Department: 1638)
Multicellular living organisms and unmodified parts thereof and
Method of introducing a polynucleotide molecule into or...
The polynucleotide contains a tissue, organ, or cell...
C435S123000, C435S193000, C435S195000, C435S233000, C435S422000, C435S468000
Reexamination Certificate
active
08053637
ABSTRACT:
Reported herein are methods for obtaining stably transformed callus inTaxus media‘Hicksii’, including particularly methods that involve using needles, stem, or bark peel as explant material for transformation. Also provided are descriptions of several promoter activities in directing reporter gene expression inTaxus mediacells, in particular cells in suspension cultures, callus and needles. Transgenic plants (e.g.,Taxusplants), plant cells, cell lines, and tissues (including seeds) are also provided, in particular those that express one or more enzymes in a paclitaxel biosynthesis pathway.
REFERENCES:
patent: 6043072 (2000-03-01), Croteau et al.
patent: 6054635 (2000-04-01), Bestwick et al.
patent: 6118049 (2000-09-01), Bestwick et al.
patent: 6288302 (2001-09-01), Yu et al.
patent: 6331416 (2001-12-01), Shani et al.
patent: 6392122 (2002-05-01), Clendennen et al.
patent: 6642438 (2003-11-01), Clendennen et al.
patent: 2004/0064854 (2004-04-01), Clendennen et al.
patent: 0017370 (2004-01-01), None
patent: WO 00/28005 (2000-05-01), None
patent: WO2005/010166 (2005-02-01), None
Furmanowa et al. Herba Polonica 44(4): 252-257 (1998).
Mathews et al. In Vitro Cellular and Developmental Biology 31(1): 36-43 (Jan. 1995).
Mathews et al. In Vitro Cellular and Developmental Biology (Plant) 28(4): 172-178 (Oct. 1992).
Fils-Lycaon et al. Plant Physiology 111(1): 269-273 (May 1996).
Han et al., “Genetic transformation of mature Taxus: An approach to genetically control the in vitro production of the anti cancer drug, taxol,”Plant Science, 95(2):187-196, 1994.
Han et al., “XXI. Genetic transformation of taxus (yew) to improve production of taxol,”Biotechnology in Agriculture and Forestry—Transgenic Trees, 44:291-306, 1999.
Jennewein et al., “Cytochrome P450 taxadiene 5alpha-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis,”Chemistry&Biology, 11(3):379-387, 2004.
Jennewein et al., “Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis,”Proceedings of The National Academy of Sciences of the United States of America, 101(24):9149-9154, 2004.
Jennewein et al., “Taxoid metabolism: Taxoid 14beta-hydroxylase is a cytochrome P450-dependent monooxygenase,”Archives of Biochemistry And Biophysics, 413(2):262-270, 2003.
Ketchum et al., “Stable transformation and long-term maintenance of transgenic Taxus cell suspension cultures,”Plant Cell Reports, 26(7):1025-1033, 2007.
Kim et al. “Expression of Modified Green Fluorescent Protein in Suspension Culture of Taxus Cuspidata,”Journal of Microbiology and Biotechnology, 10(1):91-94, 2000.
An et al., “Binary vectors,”In Plant Molecular Biology Manual, A3:1-19 (1988).
Becker et al., “New plant binary vectors with selectable markers located proximal to the left T-DNA border,”Plant Mol Biol, 20:1195-1197 (1992).
Bommineni et al., “Transformation of white spruce (Picea glauca) somatic embryos by microprojectile bombardment,” PlantCell Rep, 13:17-23 (1993).
Brincat et al., “Alterations in Taxol production in plant cell culture via manipulation of the phenylalanine ammonia lyase pathway,”Biotechnol Prog, 18:1149-56 (2002).
Chupeau et al., “Transgenic plants of lettuce (Lactuca sativa) obtained through electroporation of protoplasts,”Bio/Technol, 7:503-508 (1989).
Dong et al., “Enhanced taxane productivity in bioreactor cultivation ofTaxus chinensiscells by combining elicitation, sucrose feeding, and ethylene incorporation,”Enz Microb Tech, 31:116-121 (2002).
Ellis et al., “Expression of inducible angiosperm promoters in a gymnosperm,Picea glauca(white spruce),”Plant Mol Biol, 17:19-27 (1991).
Forward et al., “The Douglas-fir BiP promoter is functional inArabidopsisand responds to wounding,”Planta, 215:569-576 (Epub Apr. 19, 2002).
Furuya et al., “Production of tocopherols by cell culture of safflower,”Phytochemistry, 26:2741-2747 (1987).
Garcia-Guevara et al., “The mannopine synthase promoter contains vectorial cis-regulatory elements that act as enhancers and silencers,”Mol Gen Genet, 262:608-617 (1999).
Gibson et al., “Potential of plant cell culture for taxane production,” inTaxol: Science and Application, (Stuffness, ed.), pp. 71-95, Boca Raton, New York, CRC Press (1995).
Huang et al.,Yunnan Zhiwu Yanjiu, “Transformation ofTaxus brevifoliabyAgobacterium rhizogenesand taxol production in hairy roots culture,”Acta Botanica Yunnanica, 19:292-296 (1997) In Chinese, contains English abstract.
Ketchum et al., “Recent progress toward an understanding of Taxol biosynthesis in plant cell cultures,” inTowards Natural Medicine Research in the 21stCentury, (Ageta, et al., eds.), Elsevier Sciences B. V. pp. 339-348 (1998).
Klein et al., “Stable genetic transformation of intactNicotianacells by the particle bombardment process,”PNAS(USA), 85:8502-8505 (1988).
La Rue, “Studies on growth and regeneration in gametophytes and sporophytes of gymnosperms,” inAbnormal and Pathological Plant Growth, Report Symp Brookhaven National Laboratory, J. Upton, New York, pp. 187-208 (1953).
Loopstra et al., “Agrobacterium-mediated DNA transfer in sugar pine,”Plant Mol Biol, 15:1-9 (1990).
Luan et al., “Transient gus expression in zygotic embryos ofTaxus brevifolia,” In Vitro Cell Dev Biol Plant, 32:81-85 (1996).
Miki et al., “Microinjection: An Experimental Tool for Studying and Modifying Plant CellsPlant,” inDNA Infectious Agents, (Hohn et al., eds.), Springer-Verlag, Wien, Austria, pp. 249-265 (1987).
Roberts et al., “Large-scale plant cell culture,”Curr Op Biotech, 8:154-159 (1997).
Robertson et al., “Genetic transformation of Norway spruce (Picea abies(L.) Karst) using somatic embryo explants by microprojectile bombardment,”Plant Mol Biol, 19:925-935 (1992).
Sederoff et al., “Gene transfer into Loblolly pine byAgrobacterium tumefaciens,” Bio/Technology, 4:647-649 (1986).
Tabata, “Paclitaxel production by plant-cell-culture technology,”Adv Biochem Eng Biotechnol, 7:1-23 (2004).
Takeya, “Plant tissue culture of taxoids,”Taxus, (Itokawa and Lee eds.), Taylor and Francis Group, London and New York, pp. 134-150 (2003).
Tang et al., “Genetic transformation of conifers and its application in forest biotechnology,”Plant Cell Rep, 22:1-15 (2003).
Vongpaseuthe et al., “Development of a particle bombardment-mediated transient transformation system forTaxusspp. cells in culture,”American Chem Soc and American Inst of Chem Eng(Aug. 29, 2007).
Yukimune et al., “Methyl jasmonate-induced overproduction of paclitaxel and baccatin III inTaxuscell suspension cultures,”Nat Biotech, 14:1129-1132 (1996).
Zhong, “Plant cell culture for production of paclitaxel and other taxanes,”J Biosci Bioeng, 94:591-599 (2002).
Huang et al., “Agrobacterium rhizogenes-mediated genetic transformation and regeneration of a conifer:Larix decidua,” In Vitro Cell Dev Biol, 27:201-207 (1991).
Lammers Allan H.
Mathews Helena V.
Reddy Vaka S.
Dianaplantsciences, Inc.
Fox David T
Workman Nydegger
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