Taxols, their preparation and intermediates thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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549214, 549215, 549298, 549332, 549432, 549433, 549510, 549544, 549545, 556436, 556441, 556443, 556449, 560 39, 560 40, 560256, 568373, 568861, C07C 3537

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048763993

ABSTRACT:
The present invention is directed to novel taxols useful as a chemotherapeutic agent. Moreover, the present invention is directed to the process of preparing taxols and various intermediates in said process. A key intermediate is this process is 2,5-dihydroxy-2-patchoulenes. Therefore the present invention is also related to said intermediate and the process for its preparation.

REFERENCES:
patent: 3989760 (1976-11-01), Light et al.
patent: 4453000 (1984-06-01), Schulte-Elte et al.

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