Taxane derivatives, their preparation and use in oncology

Details Taxane derivatives, their preparation and use in oncology Taxane derivatives, their preparation and use in oncology

1992-05-11

1993-10-05

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 27, 560 28, C07C 6976

Patent

active

052507220

ABSTRACT:
The preparation of new 3,11-cyclotaxanes having the general formula 1. Cyclotaxane 1a (1, R'.dbd.R".dbd.H) may be isolated from plants of the genus Taxus. New cyclotaxanes 1 have antiblastic activity.

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CA 116(5): 41793t 1992.
CA 91(19): 157944n 1979.
CA 95(7): 58056a 1981.
CA 115(13): 13677j 1991.

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