Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1988-10-05
1989-10-17
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424451, 424456, 424459, 424461, 424462, 424490, 424494, 424497, A61K 954
Patent
active
048746134
ABSTRACT:
A pharmaceutical dosage unit suitable for masking the unpleasant taste of orally administered pharmaceutical agents and which facilitates swallowing comprises a plurality of subdosage units disposed within a container. Each subdosage unit is a pellet with an inner core coated with an active pharmaceutical agent, a first layer surrounding the core comprising a biologically inert excipient or filler, and a second layer surrounding the first layer comprising a mixture of a cationic copolymeric acrylate resin and a basic compound. The container of the dosage unit may be orally ingestible in itself, such as an openable gelatin capsule, or may be a frangible packet which must be opened in order to orally administer the subdosage pellets to a patient.
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Search Report Prepared for the Inventor by an Independent Searcher.
Baker Cummins Pharmaceuticals, Inc.
Page Thurman K.
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