Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Patent
1997-03-12
1998-06-30
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
514485, 554110, 554112, 560 29, 560160, 562555, A61K 31225, A61K 3123, A61K 31325, C07C27122
Patent
active
057734658
ABSTRACT:
Tartronic acid acetalic ethers and esters of the general formula: ##STR1## are provided and are useful in treatment of bone dysmetabolism. As examples, Ra and Rb may be hydrogen, B is a C.sub.2 -C.sub.12 acyl group, R is phenyl and n is 0-12.
REFERENCES:
Mannich et al., Chem. Ber., 55 (1922) 3506-3508.
Chemical Abstracts, vol. 115, No. 21, 1991, Abstract No. 232008e, Jurczak, et al, "The High Pressure Reaction of 2,5-Dimethylfuran with Activated Carbonyl Compounds".
Tetrahedron Letters, vol. 25, No. 50, 1984, pp. 5747-5750, Genner, et al, "Reactions of Furans, Thiophenes and Pyrroles with Activated Carbonyl Compounds Under Thermal and High Pressure Conditions" (see pp. 5747-5748).
Chemical Abstracts, vol. 72, No. 9, 1970, Abstract No. 42684t, J. Grandjean, "Tartronic Acids", p. 352.
Bulletin of the Chemical Society of Japan, vol. 48, No. 1, 1975, pp. 277-280, Pac, et al, "Benzoyl Peroxide- And Photo-Induced Reactions of Diethyl Mesoxalate in Cyclohexane and Toluene" (see pp. 277-279).
Chemical Abstracts, vol. 51, No. 10, 1957, Abstract No. 12085g, Mikhlina, et al, "Synthesis of 3-Methyl-2-Quinclidinecarboxylic Acid".
Tetrahedron Letters, vol. 30, No. 10, 1989, pp. 1289-1292, Citterio, et al, "Oxidative Deprotonation of Carbonyl Compounds by FE(III)Salts" (see pp. 1289-1292).
Tetrahedron, (Incl. Tetrahedron Reports), vol. 25, No. 20, 1969, pp. 4967-4981, Chottard, et al, "Cyclisation Radicalaires.XII" (see pp. 4976-4981).
Liebigs Annalen Der Chemie, vol. 2, 1990, pp. 181-183, Kawabata, et al, "Electrochemical Hydroxylation of Active Methine Compounds" (see pp. 181-183).
Chemical Abstracts, vol. 85, No. 24, 1976, Abstract No. 179401m, Abe, et al, "Dibasic Acids Containing Ether Linkages" (p. 102).
Caselli Gianfranco
Clavenna Gaetano
Cotini Lorella
Gandolfi Carmelo A.
Mantovanini Marco
Dees Jos,e G.
Dompe Farmaceutici S.p.A.
Stockton Laura L.
LandOfFree
Tartronic acids, their acetalic ethers and o-esters does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tartronic acids, their acetalic ethers and o-esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tartronic acids, their acetalic ethers and o-esters will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1859728