Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1994-11-21
1996-05-28
Parr, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303919, 530402, 530409, C07K 1600, C07K 1646, C07K 1900
Patent
active
055212905
ABSTRACT:
Targeting substance-diagnostic/therapeutic agent conjugates joined by stabilized Schiff base or hydrazone linkages are disclosed. In addition, slow release carrier-drug pharmaceuticals are described. The diagnostic and therapeutic conjugates and pharmaceuticals of the present invention provide certain advantages relating to in vivo administration, including controlled release of the active agent at a target site.
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Morgan, Jr. A. Charles
Sivam Gowsala P.
Vrudhula Vivekananda M.
Eisenschenk F. Christopher
NeoRx Corporation
Parr Margaret
Rives Stoel
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