Targeting pulmonary epithelium using ADRP

Details Targeting pulmonary epithelium using ADRP Targeting pulmonary epithelium using ADRP

2006-04-03

2011-11-29

Long, Scott (Department: 1633)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C424S450000, C424S085400, C424S649000, C514S120000, C514S559000, C514S034000, C514S283000, C514S049000, C514S109000, C514S449000

Reexamination Certificate

active

08066971

ABSTRACT:
This invention provides novel compositions and methods for the specific and/or preferential delivery of an effector (e.g. a drug or label) to an epithelial cell (e.g. a pulmonary epithelium). The compositions comprise an adipocyte differentiation-related protein (ADRP) attached to an effector thereby forming a chimeric moiety. The chimeric moiety is preferentially delivered to epithelial cells.

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