Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2006-11-20
2009-08-25
Swartz, Rodney P. (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C530S300000, C530S350000, C536S023100, C536S023700, C424S009100, C424S009200, C424S130100, C424S139100, C424S150100, C424S184100, C424S185100, C424S190100, C424S234100
Reexamination Certificate
active
07579012
ABSTRACT:
Disclosed herein are novel methods for screening for compounds useful in treating or preventing tuberculosis. In exemplary embodiments, screening methods are based on the implementation or manipulation of triacylglycerol synthase like polypeptides or polynucleotides encoding the same. The methods are useful in identifying agents active against TB infection.
REFERENCES:
Daniel, J., et al. Induction of a novel class of diacylglycerol acyltransferasces and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture. Journal of Bacteriology, vol. 186, No. 15, pp. 5017-5030, Aug. 2004.
Daniel Jaiyanth
Dubey Vinod S.
Kolattukudy Pappachan E.
Sirakova Tatiano
Beusse Wolter Sanks Mora & Maire
Swartz Rodney P.
University of Central Florida Research Foundation Inc.
Van Dyke Timothy H.
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