Targeting of MKRN1 for identifying cancer treatment agents

Details Targeting of MKRN1 for identifying cancer treatment agents Targeting of MKRN1 for identifying cancer treatment agents

2011-03-08

2011-03-08

Yu, Misook (Department: 1642)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S006120, C435S007100

Reexamination Certificate

active

07901906

ABSTRACT:
Disclosed herein are novel methods for screening for compounds useful in treating telomerase positive cancers. In exemplary embodiments, screening methods are based on the implementation or manipulation of therapeutic agents that up-regulate activity or expression of MKRN polypeptides or polynucleotides encoding the same, respectively. The methods are useful in identifying agents that can serve as cancer therapeutic agents.

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