Targeted thermal release of drug-polymer conjugates

Details Targeted thermal release of drug-polymer conjugates Targeted thermal release of drug-polymer conjugates

1994-09-26

1996-02-13

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

With means for cutting, scarifying, or vibrating tissue

128598, 12866003, 601 3, 607 97, 424 934, A61B 1720

Patent

active

054908400

ABSTRACT:
Thermal drug treatment of tumor tissue is obtained by attaching a thermally active drug to carrier molecules which have an affinity to tumor tissue. Localized heating is performed on the tumor tissue, thereby activating the drug in the tumor tissue. The end result may be concentrated delivery of a drug to a chosen tissue, or, in the case where the drug creates a toxin when heated, selective tissue destruction of a selected locations heated. The localized heat may be applied by focused ultrasound heating.

REFERENCES:
patent: Re33590 (1991-05-01), Dom
patent: 4771130 (1988-09-01), Cohen
patent: 4822335 (1989-04-01), Kawaii
patent: 4925922 (1990-05-01), Byers
patent: 4960408 (1990-10-01), Klainer
patent: 5016615 (1991-05-01), Driller
patent: 5145863 (1992-09-01), Dougherty
patent: 5163898 (1992-11-01), Marcos
patent: 5216126 (1993-06-01), Cox et al.
patent: 5230883 (1993-07-01), Kornguth
patent: 5247935 (1993-09-01), Cline et al.
patent: 5275165 (1994-01-01), Ettinger et al.
patent: 5307812 (1994-05-01), Hardy et al.
patent: 5370120 (1994-12-01), Oppelt
Pimm, Malcolm. "Critical Reviews in Therapeutic Drug Carrier Systems", vol. 5, issue 3 (1988).
Lele, P. P., "Hyperthermiaby Utrasound", M.I.T.
"The Demonstration of Human Tumors on Nude Mice Using Gadolinium-Labelled Monoclonal Antibodies for Magnetic Resonance Imaging by S.Gohr-Rosenthal, H. Schmitt-Willich, W. Ebert & J. Conrad, Investigative Radiolog", vol. 28, No. 9, 789-795.

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