Targeted liposomal constructs for diagnostic and therapeutic use

Details Targeted liposomal constructs for diagnostic and therapeutic use Targeted liposomal constructs for diagnostic and therapeutic use

1998-07-02

2000-05-16

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 121, 424 9321, 424 951, 424417, 424 943, 436829, 935 54, 514 45, 514 49, 514561, 514649, 514663, A61K 9127

Patent

active

060634006

ABSTRACT:
This invention provides a liposomal construct for delivering a diagnostic or therapeutic agent to a mammal comprising a liposomal carrier, a diagnostic or therapeutic agent entrapped within or associated with said liposomal carrier and a sequestering agent distributed within said liposomal carrier to reduce leakage of the diagnostic or therapeutic agent from the liposomal construct prior to delivery.

REFERENCES:
patent: 4659655 (1987-04-01), Rose
patent: 5049372 (1991-09-01), Rapaport
patent: 5626870 (1997-05-01), Monshipouri
patent: 5629215 (1997-05-01), Ribier

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