Targeted enternal delivery system

Details Targeted enternal delivery system Targeted enternal delivery system

1986-11-25

1990-03-20

Robinson, Ellis P.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424463, 424 45, A11K 964

Patent

active

049100211

ABSTRACT:
A capsule for oral administration of a pharmaceutically active ingredient contains a pharmaceutical composition comprising the active ingredient, for example, a peptide, an absorption promoter and usually, a carrier. The absorption promoter is capable of enhancing absorption of the active ingredient from the intestine into the bloodstream. The capsule is coated with a film forming composition, which film is sufficiently insoluble at a pH below 7 as to be capable of protecting the capsule and its contents from the digestive juices until the capsule reaches a region below the upper part of the intestine, whereupon the coating and capsule are capable of eroding or dissolving to release the active ingredient for absorption into the bloodstream.

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