Image analysis – Applications – Biomedical applications
Reexamination Certificate
2008-12-11
2011-11-22
Nguyen, Vinh (Department: 2858)
Image analysis
Applications
Biomedical applications
C382S128000
Reexamination Certificate
active
08064679
ABSTRACT:
Edges in cytological image data are identified by obtaining a digital image of a specimen and computing a gradient image from the obtained digital image. A scaling function is applied to the grayscale image to identify regions of interest (e.g., edges of cell nuclei) in the digital image. Edges of the regions of interest are then identified based on the product of the computed gradient image and the scaling image. The scaling function may be applied to each image frame and one or more scaling thresholds are established for each frame to selectively pass, suppress, or scale pixels based on their measured intensity values. The scaled image resulting from application of the scaling function is multiplied with the gradient image to produce a targeted gradient image that identifies the edges of the region of interest. The targeted gradient image isolates edges corresponding to particular cellular structures, while rejecting other edges within the image.
REFERENCES:
patent: 5016173 (1991-05-01), Kenet et al.
patent: 7218775 (2007-05-01), Kokko et al.
patent: 7450762 (2008-11-01), Morell
patent: 7457446 (2008-11-01), Soenksen
Cytyc Corporation
Nguyen Vinh
Vista IP Law Group LLP
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