Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-07-15
2008-07-15
Mondesi, Robert B. (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C514S002600, C530S300000
Reexamination Certificate
active
11254805
ABSTRACT:
The present invention is directed to methodology that allows a variety of compounds to be attached to self-assembling peptides using biotin/streptavidin linkages. The peptides can be used to form a biologically compatible membrane that promotes the growth and differentiation of cells. The attached therapeutic agents can be used to promote this process and the gel along with the growing cells can be implanted at a site in vivo where tissue repair is needed. Alternatively, membranes can be used for culturing cells in vitro or can be used for delivering drugs in vivo in the absence of seeded cells.
REFERENCES:
patent: 5670483 (1997-09-01), Zhang et al.
patent: 6548630 (2003-04-01), Zhang et al.
Segers and Lee, “Local delivery of proteins and the use of self-assembling peptides”, Drug Discovery Today 12(13/14):561-568 (2007).
Chan, et al., Effect of Streptavidin Affinity Mutants on the Integrin-Independent Adhesion of Biotinylated Endothelial Cells,Biomaterials 24:559-570 (2003).
Davis, et al., “Injectable Self-Assembling Peptide Nanofibers Create Intramyocardial Microenvironments for Endothelial Cells,”Circulation 111:442-450 (2005).
Davis, et al., “Custom Design of the Cardiac Microenvironment with Biomaterials,”Circ. Res. 97:8-15 (2005).
Fraidenraich, et al., “Rescue of Cardiac Defects inIDKnockout Embryos by Injection of Embryonic Stem Cells,”Science 306:247-252 (2004).
Li, et al., Overexpression of Insulin-Like Growth Factor-1 in Mice Protects from Myocyte Death after Infraction, Attenuating Gentricular Dilation, Wall Stress, and Cardiac Hypertrophy,J. Clin. Invest. 100:1991-1999 (1997).
Kofidis, et al., “Insulin-Like Growth Factor Promotes Engraftment, Differentiation, and Functional Improvement after Transfer of Embryonic Stem Cells for Myocardial restoration,”Stem Cells 22:1239-1245 (2004).
Livnah, et al., Three-Dimensional Structures of Avidin and the Avidin-Biotin Complex,Proc. Natl. Acad. Sci. USA. 90:5076-5080 (1993).
Neish, et al., “Direct Visualization of Ligand-Protien Interactions Using Atomic Force Microscopy,”British J. Pharmacol. 135:1943-1950 (2002).
Ohno, et al., “Cell-Specific, Multidrug Delivery System Using Streptavidin-Protien A Fusion Protien,”Biochem. Mol. Med. 58:227-233 (1996).
Palmen, et al., “Cardiac Remodeling after Mycardial Infarction Is Impaired in IGF-1 Deficient Mice,”Cardiovasc. Res. 50:516-524 (2001).
Pugliese, et al., “Three-Dimensional Structure of the Tetragonal Crystal Form of Egg-White Avidin in its Functional Complex with Biotin at 2-7 A Resolution,”J. Mol. Biol. 231:698-710 (1993).
Smith, et al., “Redirected Infection of Directly Biotinylated Recombinant Adenovirus Vectors Through Cell Surface Receptors and Antigens,”Proc. Natl. Acad. Sci. USA 96:8855-8860 (1999).
Stayton, et al., “Control of Protein-Ligand Recognition Using a Stimuli-Responsive Polymer,”Nature 378:472-474 (1995).
Torella, et al., “Cardiac Stem Cell and Myocyte Aging, Heart Failure, and Insulin-Like Growth Factor-1 Overexpression,”Circ. Res. 94:514-524 (2004).
Vasan, et al., “Serum Insulin-Like Growth Factor 1 and Risk for Heart Failure in Elderly Individuals without a Previous Myocardial Infraction: The Framingham Heart Study,”Ann. Intern. Med. 139:642-648 (2003).
Zhang, et al., “Fabrication of Novel Biomaterials through Molecular Self-Assembly,”Nature Biotech 21:1171-1178 (2003).
Zhang, et al., “Spontaneous Assembly of Self-Complementary Oligopeptide to Form a Stable Macroscopic Membrane,”Proc. Natl. Acad. Sci. USA 90:3334-3338 (1993).
Zhang, et al., “Design of Nanostructured Biological Materials through Self-Assembly of Peptides and Protiens,”Curr. Opin. Chem. Biol 6:865-871 (2002).
International Search Report for PCT/US2005/037955, published May 4, 2006.
International Preliminary Examination Report for PCT/US2005/037955, issued Aug. 28, 2007.
Davis Michael E.
Lee Richard T.
Desai Anand U
Law Offices of Michael A. Sanzo, LLC
Mondesi Robert B.
Sanzo Michael A.
The Brigham and Women's Hospital, Inc.
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