Targeted deletions using retroelement-mediated placement of...

Details Targeted deletions using retroelement-mediated placement of... Targeted deletions using retroelement-mediated placement of...

2011-04-05

2011-04-05

Marvich, Maria (Department: 1633)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

Introduction of a polynucleotide molecule into or...

C435S478000, C435S069100, C435S071100, C536S023710, C536S023720, C536S025320

Reexamination Certificate

active

07919322

ABSTRACT:
The present invention provides methods, nucleic acid constructs, and kits for selectively deleting a region of a nucleic acid sequence. Specifically, it utilizes retargeting retroelements to place site-specific recombination sites at targeted locations in the nucleic acid sequence. The region between the recombination sites is then deleted using a site-specific recombination system.

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