Chemistry: analytical and immunological testing – Biospecific ligand binding assay
Reexamination Certificate
2011-01-25
2011-01-25
Nguyen, Bao-Thuy L (Department: 1641)
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
C436S514000, C436S518000, C436S547000, C436S807000, C436S808000, C436S810000, C530S387100, C530S387300, C530S866000, C530S867000
Reexamination Certificate
active
07875465
ABSTRACT:
A capturing molecule having not less than two domains specifically binding to different sites of a target substance, wherein the not less than two domains comprise (1) a first domain having a hypervariable loop structure at a binding site to the target substance, and (2) a second domain having no hypervariable loop structure at a binding site to the target substance.
REFERENCES:
patent: 5529792 (1996-06-01), Risau et al.
patent: 5653675 (1997-08-01), Kanno et al.
patent: 5863789 (1999-01-01), Komatsu et al.
patent: 5969108 (1999-10-01), McCafferty et al.
patent: 6424418 (2002-07-01), Kawabata et al.
patent: 6472191 (2002-10-01), Yano et al.
patent: 6686439 (2004-02-01), Kenmoku et al.
patent: 6803444 (2004-10-01), Suzuki et al.
patent: 6853477 (2005-02-01), Nomoto et al.
patent: 6858417 (2005-02-01), Yano et al.
patent: 6861496 (2005-03-01), Kenmoku et al.
patent: 6864074 (2005-03-01), Yano et al.
patent: 6916861 (2005-07-01), Nomoto et al.
patent: 6951745 (2005-10-01), Nomoto et al.
patent: 7153622 (2006-12-01), Honma et al.
patent: 7166697 (2007-01-01), Galanis et al.
patent: 7235396 (2007-06-01), Nomoto et al.
patent: 2003/0088074 (2003-05-01), Hamers et al.
patent: 2003/0144483 (2003-07-01), Tempest et al.
patent: 2003/0194443 (2003-10-01), Yano et al.
patent: 2004/0005638 (2004-01-01), Honma et al.
patent: 2005/0208635 (2005-09-01), Nomoto et al.
patent: 2006/0115861 (2006-06-01), Shiotsuka et al.
patent: 2006/0172398 (2006-08-01), Nomoto et al.
patent: 2006/0172399 (2006-08-01), Nomoto et al.
patent: 2006/0275811 (2006-12-01), Hatakeyama et al.
patent: 2007/0054315 (2007-03-01), Imamura et al.
patent: 2007/0131546 (2007-06-01), Nomoto et al.
patent: 2007/0131547 (2007-06-01), Nomoto et al.
patent: 2007/0178522 (2007-08-01), Shiotsuka et al.
patent: 2007/0190590 (2007-08-01), Kubo et al.
patent: 88/06630 (1988-09-01), None
patent: 92/15606 (1992-09-01), None
patent: 02/20565 (2002-03-01), None
patent: 2004/003019 (2004-01-01), None
patent: 2005/097831 (2005-10-01), None
Cheong et al., Biochemical and Biophysical Research Communications. vol. 173, No. 3, 1990. pp. 795-800.
Conrath et al., The Journal of Biological Chemistry. vol. 276, No. 10, Mar. 9, 2001. pp. 7346-7350.
Miquel A. Andrade, et al., “Comparison of ARM and HEAT Protein Repeats”, J. Mol. Biol., vol. 309, 2001, pp. 1-18.
Alisdair B. Boraston, et al., “Carbohydrate-binding modules: fine-tuning polysaccharide recognition”, Biochem. J., vol. 382, 2004, pp. 769-781.
Stefan Ewert, et al., “Biophysical Properties of Camelid VHHDomains Compared to Those of Human VH3 Domains”, Biochemistry, vol. 41, 2002, pp. 3628-3636.
Akiko Koide, et al., “The Fibronectin Type III Domain as a Scaffold for Novel Binding Proteins”, J. Mol. Biol., vol. 284, 1998, pp. 1141-1151.
Dario Neri, et al., “High-affinity Antigen Binding by Chelating Recombinant Antibodies (CRAbs)”, J. Mol. Biol., vol. 246, 1995, pp. 367-373.
Karin Nord, et al., “Binding proteins selected from combinatorial libraries of an α-helical bacterial receptor domain”, Nature Biotechnology, vol. 15, Aug. 1997, pp. 772-777.
Stewart D. Nuttall, et al., “Isolation of the new antigen receptor from wobbegong sharks, and use as a scaffold for the display of protein loop libraries”, Molecular Immunology, vol. 38, 2001, pp. 313-326.
Erin K. O'Shea, et al., “Mechanism of Specificity in the Fos-Jun Oncoprotein Heterodimer”, Cell, vol. 68, Feb. 21, 1992, pp. 699-708.
Erin K. O'Shea, et al., “X-ray Structure of the GCN4 Leucine Zipper, a Two-Stranded, Parallel Coiled Coil”, Science, vol. 254, No. 5031, Oct. 25, 1991, pp. 539-544.
Mehmet Sarikaya, et al., “Molecular biomimetics: nanotechnology through biology”, Nature Materials, vol. 2, Sep. 2003, pp. 577-585.
Arne Skerra, “‘Anticalins’: a new class of engineered ligand-binding proteins with antibody-like properties”, Reviews in Molecular Biotechnology, vol. 74, 2001, pp. 257-275.
Arne Skerra, “Engineered protein scaffolds for molecular recognition”, Journal of Molecular Recognition, vol. 13, 2000, pp. 167-187.
Silvia Spinelli, et al., “Lateral Recognition of a Dye Hapten by a Llama VHH Domain”, J. Mol. Biol., vol. 311, 2001, pp. 123-129.
Mårten Andersson, et al., “Inclusion of a non-immunoglobulin binding protein in two-site ELISA for quantification of human serum proteins without interference by heterophilic serum antibodies”, Journal of Immunological Methods, vol. 283, 2003, pp. 225-234.
H. Kaspar Binz, et al., “High-affinity binders selected from designed ankyrin repeat protein libraries”, Nature Biotechnology, vol. 22, No. 5, May 2004, pp. 575-582.
Hatakeyama Satoru
Kaieda Masaru
Nomoto Tsuyoshi
Shiotsuka Hidenori
Yamamichi Junta
Canon Kabushiki Kaisha
Fitzpatrick ,Cella, Harper & Scinto
Nguyen Bao-Thuy L
LandOfFree
Target substance capturing molecule does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Target substance capturing molecule, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Target substance capturing molecule will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2736027