Target for regulating multiple sclerosis

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

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C424S133100, C424S143100, C424S144100

Reexamination Certificate

active

08038992

ABSTRACT:
Methods are provided for decreasing demyelinating inflammatory disease in a subject by inhibiting the activity of chemokine-like receptor 1 (CMKLR1). Methods are also provided for screening for agents that find use in treating demyelinating inflammatory disease in a subject.

REFERENCES:
Graham et al., Clinical Immunology, vol. 123 (Supplement 1), May 10, 2007, abstract No. OR.91, p. S138.
Parolini et al., Blood, vol. 109, 2007, pp. 3625-3632.
Cash et al., J. Experimental Medicine, vol. 205, Apr. 7, 2008, pp. 767-775.

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