Tapered tubular optical waveguide probe for magnetic...

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

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C436S526000, C436S073000, C436S074000, C436S533000, C436S086000, C436S063000, C436S085000, C436S164000, C436S501000, C436S534000, C436S546000, C435S007100, C435S007500, C435S007930, C435S007940, C435S007950, C435S287100, C435S287200, C435S288700, C435S281000, C435S290100, C422S082070, C422S051000, C422S068100, C422S082050, C422S050000, C422S052000, C422S082080

Reexamination Certificate

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06858440

ABSTRACT:
A waveguide probe for the detection of pathogens in a sample which comprises a laser, a first and a second tubes that converge at a point to form a proximal end. A magnet is positioned in the end to configure to focus paramagnetic microspheres attached to antigen/antibody/optically labeled antibody complexes in the field of view. The proximal end is polished to form an aperture.

REFERENCES:
patent: 5606170 (1997-02-01), Saaski et al.
patent: 5862273 (1999-01-01), Pelletier
patent: 6254830 (2001-07-01), Pivarnik et al.
Pivarnik et al. “Magnetic Focusing Immunosensor for the Datection of Salmonella typhimurium in Foods” SPIE, 3544, 41-49 (Jan. 1999).

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