Tao protein kinases and methods of use therefor

Details Tao protein kinases and methods of use therefor Tao protein kinases and methods of use therefor

1998-04-14

2000-12-26

Prouty, Rebecca E.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Transferases

435194, A61K 3851, C12N 912

Patent

active

061654612

ABSTRACT:
Compositions and methods are provided for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.

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