Tango 240 polypeptides and uses thereof

Details Tango 240 polypeptides and uses thereof Tango 240 polypeptides and uses thereof

2007-10-16

2007-10-16

O'Hara, Eileen B. (Department: 1646)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S192100, C530S350000, C536S023500, C536S023400, C514S012200

Reexamination Certificate

active

10929150

ABSTRACT:
The invention provides isolated nucleic acid molecules, designated TANGO 228 nucleic acid molecules, which encode secreted proteins with homology to the rat MCA-32 protein, isolated nucleic acid molecules, designated TANGO 240 nucleic acid molecules, which encode secreted proteins with homology to the Mycobacterium tuberculosis hypothetical protein Rv0712, and isolated nucleic acid molecules, designated TANGO 243 nucleic acid molecules, which encode proteins with homology to human PLAP (phospholipase A2-activating protein).The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

REFERENCES:
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patent: WO 99/06439 (1999-02-01), None
patent: WO 99/33982 (1999-07-01), None
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“Hypothetical protein.” May 1, 1997 (sequence) UniProt [online] The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 ISD, UK. Retrieved from the Internet. URL: http://www.ebi.ac.uk/>. UniProt Accession No. P95060.

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