Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1999-08-06
2000-12-26
Richter, Johann
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
568309, 568338, 568700, 568810, 568814, 549476, 560 60, 560184, 562401, 562450, 564385, C07C 29143, C07C 29136, C07C 2978, C07C 2992
Patent
active
061662607
ABSTRACT:
The present invention relates to a tandem process of reduction and host-guest complexation using metal-hydride complexes to reduce chemical entities bearing carbonyl groups or their equivalents, and host-guest complexation to achieve improved optical resolution of the reduction product. In the complexation step, the reduction product is optically resolved via inclusion into the crystalline complex where it resides as guest and another complex component acts as host. Additional crystallization stages are performed if further improvements in the enantiomeric excess is desired.
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Davis Brian J.
Richter Johann
Zeeland Chemicals, Inc.
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