Tandem ionizer ion source for mass spectrometer and method...

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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C250S281000, C250S282000

Reexamination Certificate

active

07939798

ABSTRACT:
An ion source a first ionizer comprising: an electrospray needle comprising a tip; and a conduit disposed annularly about the needle and configured to pass an inert gas in proximity of the tip to nebulize a fluid emerging from the tip, the nebulized fluid comprising analytes and a mobile phase. The ion source comprises a capillary in tandem with the first ionizer and configured to receive the droplets; a heater configured to heat the capillary to a temperature at which mobile phase vaporizes; and a second ionizer in tandem with the capillary and configured to receive the vaporized mobile phase and the analytes. A method is also described.

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Related to co-pending U.S. Appl. No. 12/346,089.
Related to co-pending U.S. Appl. No. 11/932,835.
R.B. Cole, “Some tenets pertaining to electrospray ionization mass spectrometry” Journal of Mass Spectrometry 35, 763-772 (2000).
D.M. Lubman ed. “Lasers and Mass Spectrometry”, Oxford University Press, 1990, pp. 223,231.

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