Taliscanin and other aristolactams for treating neurological dis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3140

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active

047820772

ABSTRACT:
A method of treating neurological disorders, in particular Parkinson's disease, is disclosed. The method involves administering an aristolactam, especially Taliscanin, an extract of the root of Aristolochia Taliscana, to an afflicted patient. The dosage is varied in accordance with the patient's response, and generally ranges from 300 to 4000 micrograms per day. Taliscanin has also been shown effective in treating Alzheimer disease and impotence.

REFERENCES:
"The Aristolochic Acids and Aristolactams", Journal of Natural Products, vol. 5, No. 5 (1982), by D. B. Mix et al.
"Tumor Inhibitors x. Photochemical Synthesis of Phenanthrenes Synthesis of Aristolochic Acid and Related Compounds", Journal of Organic Chemistry, vol. 30, by S. M. Kupchan and H. C. Warmser.
"The Aristolochic Acids and Aristolactams," Isoquinoline Alkaloid Research, Plenum Press, Chapter 17 (1978), by Channer.
Nervous System, "A Strategic Approach to Parkinson's", Emergency Medicine, 95-11 (Apr. 30, 1987), by J. Fermaglich.
Las Aristoloquias Medicinales, Anales de el Instituto Medico Nacional Mexicod, Mexico D. F., Tomo VIII, 16.
"La Taliscanina, un Componente De Aristolochia Taliscana", Cincia Mexico, vol. 24, by L. Maldanado et al.

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