Tagged gibberellins

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

71 89, C07D30777

Patent

active

042821541

ABSTRACT:
As per invention, [6--.sup.3 H] or [6--.sup.2 H] gibberellins respectively are produced. By the process as per invention, production of tagged gibberellins is made from natural gibberellins or gibberellin derivatives having a carboxyl group at position 6 of the ent-gibberellin basic skeleton. After transformation into a gibberellin derivative with a hydroxymethyl group at position 6, oxidation is made to gibberellin-7-aldehyde with subsequent conversion of same to a mixture of 6-epimeric gibberellin-7-aldehydes, which will be obtained tagged at the C-6 position if deuterium or tritium donors are present during epimerization, oxidation into tagged gibberellins being performed thereafter.
By the invention, tagged gibberellins are made available which are tritiated or deuterated to such a C-H bond as is present in unsubstituted state in all natural gibberellins and their derivatives, and at which bond no biochemical changes have hitherto been observed.
The process as per invention is of general applicability and produces the tagged gibberellins with a high yield. The process is particularly suitable for compounds with acid-sensitive structure characteristics, for example with simultaneous presence of a hydroxyl group at the C-13 position and of a .DELTA. 16.17 double bond.

REFERENCES:
Murofushi et al., Agric. Biol. Chem., 38(2), 475-476, 1974, S583 A37.
Murofushi et al., Agric. Biol. Chem., 41(6), 1075-1079, 1977, S583 A37.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Tagged gibberellins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tagged gibberellins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tagged gibberellins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-239592

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.