Surgery – Controlled release therapeutic device or system
Patent
1994-04-25
1995-11-14
Rosenbaum, C. Fred
Surgery
Controlled release therapeutic device or system
A61M 3500
Patent
active
054662338
ABSTRACT:
A tack for intraocular drug delivery and a method for insertion and removal of an intraocular device for sustained release of a drug are provided. The tack comprises a post, an anchoring region and a head. The post is for being positioned within the vitreous region of the eye. The post has a first end and a second end, and includes a drug to be administered. The anchoring region is affixed to the second end of the post, and includes a width measured perpendicularly to a longitudinal axis of the tack which varies to provide the anchoring region with a configuration to anchor the tack within at least one of a sclera, a retina and a choroid. The head extends radially outwardly from the anchoring region such that upon insertion of the anchoring region and post within the eye, the head remains external to the eye and abuts a scleral surface of the eye. Other embodiments include a tack comprising a post, a central portion, a head and a suture hole through the head for anchoring the head to the sclera. Alternatively the tack comprises a post having a first portion of liquid drug, a hollow central portion filled with a second portion of liquid drug in fluid communication with the post and a head with an opening which allows for injection of subsequent doses of liquid drug through the head into the central portion.
REFERENCES:
patent: 3828777 (1974-08-01), Ness
patent: 3845201 (1974-10-01), Haddad
patent: 3914402 (1975-10-01), Shell
patent: 3926188 (1975-12-01), Baker et al.
patent: 3949750 (1976-04-01), Freeman
patent: 3995635 (1976-12-01), Higuchi et al.
patent: 4014335 (1977-03-01), Arnold
patent: 4034758 (1977-07-01), Theeuwes
patent: 4135514 (1979-01-01), Zaffaroni et al.
patent: 4164559 (1979-08-01), Miyata et al.
patent: 4179497 (1979-12-01), Cohen et al.
patent: 4186184 (1980-01-01), Zaffaroni
patent: 4300557 (1981-11-01), Refojo et al.
patent: 4343787 (1982-08-01), Katz
patent: 4439198 (1984-03-01), Brightman, II et al.
patent: 4634418 (1987-01-01), Binder
patent: 4712550 (1987-12-01), Sinnett
patent: 4730013 (1988-03-01), Bondi et al.
patent: 4774091 (1988-09-01), Yamahira et al.
patent: 4851228 (1989-07-01), Zentner et al.
patent: 4863457 (1989-09-01), Lee
patent: 4979938 (1990-12-01), Stephen et al.
patent: 5049142 (1991-09-01), Herrick et al.
patent: 5098443 (1992-03-01), Parel et al.
patent: 5141748 (1992-08-01), Rizzo
patent: 5147647 (1992-09-01), Darougar
patent: 5164188 (1992-11-01), Wong
patent: 5171270 (1992-12-01), Herrick
patent: 5238687 (1993-08-01), Magruder et al.
patent: 5277912 (1994-01-01), Lowe et al.
patent: 5334189 (1994-08-01), Wade
I. M. Katz et al., "A Soluble Sustained-Release Ophthalmic Delivery Unit", 8:5 (May 1977) pp. 728-734.
D. W. Lamberts, M.D. et al., "A Clinical Study of Slow-Releasing Artificial Tears", Ophthalmology 85 (1978) pp. 794-800.
P. Wright et al., "Slow-release Artificial Tear Inserts in the Treatment of Dry Eyes Resulting from the Oculomucocutaneous Syndrome", British Journal of Ophthalmology 67 (1983) pp. 393-397.
D. A. Lee et al., "Glaucoma Filtration Surgery in Rabbits Using Bioerodible Polymers and 5-Fluorouracil", Ophthalmology 94:12 (1987) pp. 1523-1530.
D. A. Lee et al., "The Use of Bioerodible Polymers and 5-Fluorouracil in Glaucoma Filtration Surgery", Investigative Ophthalmology & Visual Science 29-11 (1988) pp. 1692-1697.
T. Moritera et al., "Microspheres of Biodegradable Polymers as a Drug-Delivery System in the Vitreous", Investigative Ophthalmology & Visual Science 32-6 (1991) pp. 1785-1790.
G. E. Sanborn et al., "Sustained-Release Ganciclovir Therapy for Treatment of Cytomegalovirus Retinitis", Arch. Ophthamol. 110 (1992) pp. 188-195.
T. J. Smith et al., "Intravitreal Sustained-Release Ganciclovir", Arch. Ophthamol 110 (1992) pp. 255-258.
A. L. Weiner, "Chapter 13: Polymeric Drug Delivery Systems for the Eye", Polymeric Site-Specific Pharmacotherapy, pp. 315-346, Edited by A. J. Domb (1994) John Wiley & Sons Ltd.
C. W. Breslin et al., "Chapter 7. Slow Release Artificial Tears", Symposium on Ocular Therapy pp. 77-83.
Johnson Sterling
Sinnett Kevin
Weiner Alan L.
Escalon Ophthalmics, Inc.
Mendez Manuel
Rosenbaum C. Fred
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