Tachykinins antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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564123, 564149, 564 80, 564 82, 514616, 514601, A61K 3115, C07C23365

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active

058497951

ABSTRACT:
The present invention refers to tachykinins antagonists of general formula (I) ##STR1## their preparation and pharmaceutical compositions containing them.

REFERENCES:
Villalgordo, J.M. et al.: Reaction of 3-Amino-2H-azirines with 2-Amino-4, 6-dinitrophenol: Synthesis of Quinazoline and 1,3-Benzoxazole Derivatives. Helv. Chim. Acta. vol. 73, pp. 959-974, 1990.
Crisma, M. et al: Structural Versatility of Peptides from C.sup..alpha. -Dialkylated Glycines. Macromolecules, vol. 21, pp. 2071-2074, 1988.

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