Tachykinins antagonists

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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514419, C07D20904, A61K 31405

Patent

active

056987102

ABSTRACT:
The present invention refers to tachykinins antagonists of general formula (I) ##STR1## their preparation and pharmaceutical compositions containing them.

REFERENCES:
Gaso et al., European J. of Pharmacology, 254 221-227 (1994).
Mantyh et al. Proc. Natl. Acad Science USA Neurobiology, vol. 85, pp. 3235-3239, May, 1988.
Hamel et al., Can. J. Physiol. Pharmacol. vol. 66, 1361-1367 (1988).
Hagiwara et al., J. Med. Chem., 36, 2266-2278 (1993).
Regoli et al., Pharmacology, 28, 301-320 (1984).
Peters et al., Amer. Review of Respiratory Disease, vol. 145, No. 4, Apr. 1992 Intl. Conference.

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