Tachykinin receptor antagonists, isoquinolones and their product

Details Tachykinin receptor antagonists, isoquinolones and their product Tachykinin receptor antagonists, isoquinolones and their product

1993-04-13

1996-06-04

Geist, Gary

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546141, C07D21538, A61K 3147

Patent

active

055233058

ABSTRACT:
Novel composition represented by the formula: ##STR1## wherein ring A and ring B each means a benzene ring which may be substituted; R means a hydrogen atom or an alkyl group which may be substituted; R.sup.1 means a hydrogen atom or an alkyl group which may be substituted; R.sup.2 means a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted, or R.sup.1 and R.sup.2, taken together with the adjacent nitrogen atom, jointly form a ring which may be substituted, or a pharmaceutically acceptable salt thereof which is a useful tachykinin receptor antagonist.

REFERENCES:
patent: 2647902 (1953-08-01), Aschner
patent: 2809969 (1957-10-01), Speeter
patent: 3247212 (1966-04-01), Johnson
patent: 3600394 (1971-08-01), Coyne
patent: 3980655 (1976-09-01), Kunstmann

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