Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-09-07
1997-03-11
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514415, 514421, 514406, 514407, 514359, 514255, 514 80, 544371, 544373, 544144, 544131, 544140, 544143, 5483611, 548491, 546201, 546199, 546194, 5462757, 5462774, 5462747, 546256, 546 22, 546 24, 424 91, C07D41906, C07D20110, A61K 3140, A61K 31495
Patent
active
056101767
ABSTRACT:
The invention concerns tachykinin antagonists. The compounds are alcohols, amines and prodrugs of nonpeptides which have utility in treating disorders mediated by tachykinins. Such disorders are respiratory, inflammatory, gastrointestinal, ophthalmic, allergies, pain, vascular, diseases of the central nervous system, and migraine. Methods of preparing compounds and novel intermediates are also included.
The compounds are expected to be especially useful in asthma, multiple sclerosis, rheumatoid arthritis, the management of pain, migraine, and antiemetic agents.
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Horwell David C.
Howson William
Pritchard Martyn C.
Anderson Elizabeth M.
Springer David B.
Warner-Lambert & Company
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