Tablets with controlled-rate release of active substances

Details Tablets with controlled-rate release of active substances Tablets with controlled-rate release of active substances

1993-09-21

1995-06-06

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424480, 424482, A61K 936, A61K 932

Patent

active

054221234

ABSTRACT:
Tablets with zero order controlled-rate of release of the active substances, consisting of a core of defined geometrical form containing the active substance, polymer substances which swell on contact with aqueous liquids and polymer substances with gelling properties, and a support applied to said core to partly cover its surface, the support consisting of polymer substances which are slowly soluble and/or slowly gellable in aqueous liquids, plasticizing substances, and possibly substances with an adjuvant function.

REFERENCES:
patent: 4218433 (1980-08-01), Kooichi et al.
patent: 4839177 (1989-06-01), Colombo et al.
patent: 4865849 (1989-09-01), Conte et al.
patent: 4892742 (1990-01-01), Shah
patent: 4933186 (1990-06-01), Ohm et al.

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