Tablets coated with aqueous resin dispersions

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 32, A61K 932

Patent

active

040605981

ABSTRACT:
Coated tablets are prepared by applying to a core of active material, at least one layer of a coating composition made up of a film forming aqueous synthetic resin dispersion and from 2-50% by weight of a water or alkaline soluble material and thereafter permitting the coating composition layer to dry. The resulting coated tablet has a core surrounded by a continuous porous matrix of synthetic resin formed from the aqueous dispersion which is insoluble in water and insoluble in the gastrointestinal tract. The pores of the continuous resin matrix are filled with a discontinuous particulate material which is water or alkaline soluble. The coated tablet initially is air and moisture tight.

REFERENCES:
patent: 3275518 (1966-09-01), Endicott et al.
patent: 3420931 (1969-01-01), Daum et al.
patent: 3538214 (1970-11-01), Polli et al.

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