Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1995-10-17
1997-06-24
Cooney, Jr., John M.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424468, 424480, 424489, 424493, 424494, 427 218, 427 219, 427 221, A61K 932, C08K 534
Patent
active
056415133
ABSTRACT:
A method for coating pharmaceutical tablets is disclosed in which polymeric coating ingredients are combined with saccharides in a melt spinning operation to form composite particulates. The particulates are then dispersed in water to form an aqueous polymer coating solution, followed by application to pharmaceutical tablets by such methods as spray coating. The particulates dissolve extremely rapidly in water to form a dispersion of the polymer coating ingredients. Such rapid dissolution allows for increased processing rates and avoids disadvantages of the prior art such as the requirement of high sheer rate mixing for long times.
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Denick, Jr. John
Lech Stanley
Atkins Michael J.
Cooney Jr. John M.
Warner-Lambert & Company
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