TAB1 protein and DNA coding therefore

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435 6, 435 71, 536 231, 530300, 530350, C12Q 168, G01N 3353, C07H 2104, C12N 900, C07K 500

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active

061400424

ABSTRACT:
TAB1 protein having activity which activates factor TAK1 in the TGF-.beta. signaling pathway, and having the amino acid sequence shown in FIG. 1.

REFERENCES:
Shibuya, et al., "Is AMK-1 a Transfer Molecule Involved in TGF-.beta. Signal Transduction," 68th Meeting Of Japanese Society (Sep. 15-18, 1995; Summary Published Jul. 25, 1995 Sendai, Japan).
Nishida, et al, ."Signaling Pathways and Functions of the MAP Kinase Superfamily," 54th Meeting Of Japanese Cancer Association, (Oct. 3-5, 1995 Koyoto, Japan).
Irie, et al., "A Novel Member of MAPKK, TAK1, May Function As A Mediator In TGF-.beta. Signal Transduction," 18th Meeting Of Japanese Molecular Biochemistry Society S21-4 and 2E11, Dec. 6-9, 1995 Nagoya, Japan.
Yamaguchi, et al., "Identification of a Member of the MAPKK Family as a Potential Mediator of TGF-.beta. Signal Transduction," Science 270:2008-11 (1995).
Shibuya, et al., "TAB1: An Activator of the TAK1 MAPKKK in TGF-.beta. Signal Transduction," Science 272: 1179-82 (1996).

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