TAB1 protein

Details TAB1 protein TAB1 protein

1996-11-20

1998-11-17

Eliott, George C.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530324, C07K 200, C07K 1400

Patent

active

058378197

ABSTRACT:
TAB1 protein having activity which activates factor TAK1 in the TGF-.beta. signaling pathway, and having the amino acid sequence shown in FIG. 1.

REFERENCES:
Shibuya, et al., "Is AMK-1 a Transfer Molecule Involved In TGF-.beta. Signal Transduction," 68th Meeting Of Japanese Society (Sep. 15-18, 1995; Summary Published Jul. 25, 1995 Sendai, Japan).
Nishida, et al., "Signaling Pathways and Functions of the MAP Kinase Superfamily," 54th Meeting Of Japanese Cancer Association, (Oct. 3-5, 1995 Koyoto, Japan).
Irie, et al.,"A Novel Member of MAPKK, TAK1, May Function As A Mediator In TGF-.beta. Signal Transduction," 18th Meeting Of Japanese Molecular Biochemistry Society S21-4 and 2E11, Dec. 6-9, 1995 Nagoya, Japan.
Yamaguchi, et al., "Identification of a Member of the MAPKK Family as a Potential Mediator of TFG-.beta. Signal Transduction, " Science 270; 2008-11 (1995).
Shibuya, et al., "TAB1: An Activator of the TAK1 MAPKKK in TGF-.beta. Signal Transduction," Science 272: 1179-82 (1996).

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