T2R taste receptors and genes encoding same

Details T2R taste receptors and genes encoding same T2R taste receptors and genes encoding same

2006-09-12

2006-09-12

Andres, Janet L. (Department: 1649)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S006120, C435S007210, C435S069100, C435S252300, C435S325000, C436S501000, C530S350000, C514S002600

Reexamination Certificate

active

07105650

ABSTRACT:
Newly identified mammalian taste-cell-specific G Protein-Coupled Receptors and the genes encoding said receptors are described. Specifically, T2R taste G Protein-Coupled Receptors that are believed to be involved in bitter taste sensation, and the genes encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular tastant in a mammal are also described, as are methods for generating a novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes.

REFERENCES:
patent: WO 99/42470 (1999-08-01), None
Perruccio and Kleinhaus, Society for Neuroscience Abstracts 26(1-2) Abstract No. 66.15, 2000.
Chandrashekar et al., Cell 100(703-711)2000.
Bowie et al., 1990, Science 247:1306-1310.
Alexander et al., Proc. Natl. Acad. Sci. 89(3352-3356)1992.
Hoon et al., Cell 96(541-551)1999.
Lindemann, B. Nature Neuroscience 3(2)99-100, 2000.
Brenner et al. PNAS 95(6073-6078)1998.
Guo-HH et al. PNAS 101(25)9205-9210, 2004.
Horrobin, DF, British Med. Journal, 322(7280)239, Jul. 2003.
Lahana R., Drug Discovery Today, 4(10)447-448, 1999.

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