Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...
Patent
1995-03-27
1998-11-03
Low, Christopher S. F.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Animal cell, per se, expressing immunoglobulin, antibody, or...
536 231, 424 732, 5303877, 435 60, 435 723, 435323, 4353201, 4354723, 435 691, C12N 500
Patent
active
058307559
ABSTRACT:
The present invention provides nucleic acid sequences for T-cell receptors which recognize tumor associated antigens. In particular, T-cell receptors which recognize melanoma antigens. This invention also provides T-cells expressing the antigen specific T-cell receptors. In addition, this invention provides stem cells expressing the antigen specific T-cell receptors or chimeric receptors. This invention further relates to therapeutic and diagnostic compositions and methods employing the T-cell receptors and chimeric receptors provided herein.
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Nishimura Michael
Rosenberg Steven A.
Low Christopher S. F.
Nguyen Dave T.
The United States of America as represented by the Secretary of
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