T cell growth factor glycoproteins

Details T cell growth factor glycoproteins T cell growth factor glycoproteins

1988-09-19

1993-05-04

Moezie, Fatemeh T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514 21, 530395, 530397, 530399, 530351, 424 851, 930141, 930140, A61K 3736, C07K 1514

Patent

active

052082180

ABSTRACT:
The present invention relates generally to a T cell growth factor. More particularly, the present invention relates to a T cell growth factor which comprises a glycoprotein which supports interleukin 2- and interleukin 4-independent growth of helper T cells. Even more particularly, the present invention relates to the helper T cell growth factor P40, pharmaceutical compositions thereof and antibodies thereto. The present invention also contemplates a method for inducing the proliferation of helper T cells. The helper T cell growth factor contemplated herein is useful in the stimulation of specific cells in the immune system.

REFERENCES:
patent: 5006459 (1991-04-01), Kung
Yang et al., blood 74(6): 1880-1884 (Nov. 1, 1989).
Renauld et al., Cytokines 2(1): 9-12 (Jan. 1990).
Renauld et al., J. Immunol. 144(11): 4235-4241 (Jun. 1990).
Druez et al., J. Immunol. 145(8): 2494-2499 (Oct. 1990).

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