T cell activation markers

Details T cell activation markers T cell activation markers

1988-02-18

1991-03-19

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 28, 536 29, C07H 1700

Patent

active

050012304

ABSTRACT:
A polypeptide designated H400 and its encoding nucleic acid are provided as markers specific for activated human T cells. Activated t cells are detected immunochemically by monoclonal antibodies specific for H400 or its immunogenic peptides. Activated T cells are also detected by nucleic acid probes directed to messenger RNA encoding the H400 protein.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
patent: 4483920 (1984-11-01), Gillespie et al.
Epes et al., Pnas, 85.9784-9708, 1888.
Angerer et al., Genetic Engineering, vol. 7, pp. 43-65, (1985).
Wolpe et al., J. Exp. Med., vol. 167, pp. 570-581 (1988).
Burd et al., J. Immunol., vol. 139, pp. 3126-3131 (1987).
White et al., J. Biol. Chem., vol. 257, pp. 8569-8572 (1982).
Southern, J. Mol. Biol. vol. 98, pp. 503-517 (1975).
Thomas, Proc. Natl. Acad. Sci., vol. 77, pp. 5201 -5205 (1980).
Obaru et al., J. Biochem., vol. 99, pp. 885-894 (1986).

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