Systems for separating high hematocrit red blood cell concentrat

Details Systems for separating high hematocrit red blood cell concentrat Systems for separating high hematocrit red blood cell concentrat

1995-08-09

1998-06-09

Kim, John

Liquid purification or separation

Casing divided by membrane into sections having inlet

Membrane movement during purification

210 85, 210 90, 210 97, 210109, 210134, 210143, 21032168, 21032178, 21032187, 604 4, 604 5, 604 6, 604 65, 604 67, A61M 126, B01D 6100, B01D 6118, B01D 6122

Patent

active

057627916

ABSTRACT:
Blood separation systems and methods utilize a membrane separation device comprising a gap between a microporous membrane and a surface facing the microporous membrane, one of the microporous membrane and the surface being rotatable relative to the other to cause separation of whole blood in the gap into plasma and concentrated red blood cells. The systems and methods include an inlet pump element coupled to the membrane separation device to convey whole blood having a known beginning hematocrit value into the gap for separation. The systems and methods also include a drive element coupled to the membrane separation device to cause rotation of the rotatable one of the microporous membrane and the facing surface. The systems and methods command the inlet pump element and the drive element as a function of the known beginning hematocrit value. This command technique obtains concentrated red blood cells having a high end hematocrit value that remains substantially constant despite variances in the known beginning hematocrit value, and, in particular, when the known beginning hematocrit value is low.

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