Systems for applying cross-linked mechanical barriers

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

Reexamination Certificate

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C604S104000, C604S096010, C604S915000, C606S215000

Reexamination Certificate

active

06994686

ABSTRACT:
A delivery device applies a biocompatible and biodegradable barrier material to a tissue region, e.g., to seal a vascular puncture site. The material comprises two liquid components, which are pre-packaged in individual dispensers. Upon mixing, the liquid components cross-link to create a barrier matrix. A holder attaches to the delivery device. The holder mutually supports the first and second dispensers while the protein solution and polymer solution are conveyed from the dispensers into a fluid delivery channel. The protein and polymer solutions mix as a result of flow through the channel.

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Transactors: Society for Biomaterials: Protoelytically Degradable Hydrogels; West et al (1997).

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